Unraveling the Impact of Salbutamol Polytherapy: Clinically Relevant Drug Interactions

نویسندگان

چکیده

The proper drug choice determines the treatment quality for a disease. pharmacotherapeutic strategy respiratory diseases often involves combination of different drugs with mechanisms action. Salbutamol is short-acting β2-agonist (SABA) used as reliever in asthma and frequently paired inhaled corticosteroids (ICS). Indeed, drug–drug interactions (DDI) receive special attention they are some most common causes adverse effects can lead to increased morbidity mortality. DDIs occur patients undergoing polytherapy at pharmacokinetic (PK) or pharmacodynamic (PD) level. Given this, interaction salbutamol other has been extensively explored terms PD PK since its introduction into pharmaceutical market. To date, more than thousand have reported. Here, we propose review such beta-blockers, anticholinergics, classes bronchodilators, corticosteroids, others, point out significant gaps knowledge DDI.

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ژورنال

عنوان ژورنال: Future Pharmacology

سال: 2023

ISSN: ['2673-9879']

DOI: https://doi.org/10.3390/futurepharmacol3010019